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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fab2e67cb0f505ca8a36fb870b9b330352af33c77b18dbf2f02cc2a224b08d' 
  AND token = 's3sVEqr+opANjB93zUWxQiPEcYa1TWDg+uWyiJZstYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}