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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14fb8e5b566c66dac44596d81387a75174783be652a8c57059000842b2297c6a' 
  AND token = 'XHcYhOXKt0zURHJ++iu5xER1SbUI46glZfgUl520Qf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}