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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f740251184b6da88df1b42aab6c674078f838204c3adf90ba004e399918aeb' 
  AND token = 'N2RV4omsbu4+xP4dJ+1WeutMz8+gWoBk4XNEFbugkAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}