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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '757eb914dbf0e889a2d994bc9fc5d222e95d2b6b7e0700cb1ff05892ca022690' 
  AND token = 'eI0Z7aAK0MYl1sZYB/IORmR6vMb8UNoICkwx0wGbPo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}