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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd497e98039796e37b5c8fd532cffafa997cdf0dd462c77b4653d3761056f38' 
  AND token = 'WhykBGKOx6pg1obdZaUGokt+sI4OJobDYpGmolleCkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}