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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1008c821f093a95e8f9daf7288a3972b97c3e3c35c954c021238467058f772d' 
  AND token = 't3KGQdM+dSJBeg2M77A2OYcTmPlRJiGm1d/npQPl5zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}