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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e124868e74b64630f03b05b4593b0336343da2d44c4a73835f07b0b488495f8' 
  AND token = 'mXhphaj/5kU2Zjtb+vxflF1RSdiF9EuD10NZc2na0DI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}