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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4907ad45f5695a1b4ae056cb7ffabdfcefc2362607db1447340f3c74188489d0' 
  AND token = '370h8idWhxA8KA5tLTYlSom5Em17hiyy4qOkK5JbApw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}