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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306e74043b3bf1b154a29ee92ab4df92c8331492d6fa50eccc5228126c5c0499' 
  AND token = 'Dux/hZF09iHIblyzNhmMH7s8GyOCcrst6m+c4u23VJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}