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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800f0dffc5cc086a6adb49eb4b2bf56af0f3c7b06afbd13bc70ea5d73a0ec530' 
  AND token = 'CgmOVW+sQGeyedgZl344SaHKlCXExoDuN2HmEAfiY60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}