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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5464376262366cc8605e13fe2804b8234ecb230b740eb698758e8f4e77db7f10' 
  AND token = 'pwumt0OXvwxDSO93wEcI338y0d0/eupmsnZtk//PZCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}