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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cafa8778a60b6a097a2bb6f1772c8fc5df7fbcc821a15f65930ad5057294027' 
  AND token = '9s2vd6EWkMdz1/mJPhPWodbSWLp7RmREW7MEeZaETac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}