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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8a48b2fc4383413e93c22e87b4cc1d6b72d390d1837e7c3449c330e31f4830' 
  AND token = 'GWvpNZ3ufA3J1F+afGCYjVUr0g+vNGLKew1q84KezWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}