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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e06a97fd0881bb14e03d8d645868c8e86c08a497f45bb6e5454b9de48a9c74' 
  AND token = 'F8mZmFW3Rwk6jJuGrSRi5hRrlS+tTQW5RLTJs7HNj1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}