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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '951dad63e982fcd516c22d66ed19d2e7bf54350c9e05b8551f512983552a4498' 
  AND token = 'xOD/HEmBbNN19jwnfDUR5k+FvjRxHoZ9U9rVoVMTqhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}