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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6484389e74c1f75508a3169043bc4be2b950ea81d1eb4e98e38280825844f4ba' 
  AND token = 'r3rneazM/b1W6Ojl2KfxSxiaJ5oZTzQ4wFUA2+SWRIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}