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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849f0932be5db6b208a1ce3f7f4560bf9d20b2916798d95b39492583b8449611' 
  AND token = 'H+P3vu5X0Cbz9Y+/hGxdSfS4RrhmCxu6tjIlEO1/bOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}