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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26cad8d1422467bef89937b6b69ef14903793225e494a1ec81d7e23e9c63e09f' 
  AND token = 'VPlKQ6lQVYSWbe+x8fUt52OeDjSjojRUPc6s0AMKmX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}