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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c61dfc72adb5b1da72365dfb342ba6f649d95f5bafb60a16b27cc0a2dc3154d' 
  AND token = '4JVrwgBuUofeWY65yJFeMg9B4fJX86zN3YWh5YJ7ctM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}