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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e217ec817b7db06f788851ad53ab38a797198755da35bb5be92cdc6e4a5281' 
  AND token = 'q4aPe/n7TcL7dhv+I1OcvI1LGbHyy7Ey67x5v7ugqtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}