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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e25d22544cf381af6e4e34dc137da3d4cf2b5b50815508bb2fda03f59ff90c6' 
  AND token = 'H0XCcIzWbNLJCTNzz2oD4vnxHDk0uqK/W9HR8/DN9tQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}