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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cb86ac43413ab0145744bb280c438ef0955039e9ad55a8f68dacafe5db65ea4' 
  AND token = 'F9ooz3YvkLuebOQRDw/0oCVU0yp2WaBSF/EnZzvhYKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}