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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ec76b9e453c2fe3d30533aa9f25f9859bebaf35d4d98c528f2876f8383bf49' 
  AND token = 'NhMYhBJZJwEc9I095Z9UIfvozLv0Jk1g4Lxlw2UOF8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}