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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df930ed1e688c1bbdda072ee2e4ced40f917325dd2a9f0494deab5cd22c0500' 
  AND token = 'p5gLPsKkoza2LXb87s9QAMufCwdir+hQl4fYy9DWqpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}