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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7b916b0b199255ef1ad72f58ad0f5bf543417be33afbe1874a6586a8f2d590' 
  AND token = 'ynsQVEzfwh6z7KMJtA1mUtRlHfLqkYWUTIDQGR0UU18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}