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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '627aca01cec736efe3176a9ff5f6a7c1cfa554999ef5f4806cc1581afb851254' 
  AND token = 'D3q3tiSeVmtlPD+j6quCZ4eHXnYMmIefuA7daR3JejY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}