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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e4d0df27341ce272cca060eef2c41bb1b1152abb2f42e57d33a09d893feb562' 
  AND token = 'ErCCOGgtLclPMZZVJeAJ19lVSv05lTgQjdVZHuILSWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}