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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a348516a6ffb2c51eb1163d2b0a58b6e398e72eed5818843c50a5500566f437c' 
  AND token = '0QKkCA/vY9BayeuzuFJc9S5eDqwWvQHNdt+ajWYRkUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}