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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2783823a43e3697346af0abd2b66dcf1fa791e3dede667bbc32adf3055b90193' 
  AND token = 'vEDB8i1tMqI3T2bolPQI3+8k1ePrF3bW0N5GFJlIaX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}