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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac5d33cfc8a164848dc5b57306258d2d639e16d5d3f35d27bcb7e83b3008cc4' 
  AND token = 'OC9B6VuZ15O1uWuW/3eVBc/AqLIb1ztscU+xjPfS5w0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}