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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11c5e781f62abdaaf92c3e2d193688670df23af4bfa4fff8a359286c7de091a3' 
  AND token = '175J+RTKL3cKGYBl4L7oNEbru5awIVVfr0moFnE5aV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}