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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd35eff3e0d43f1b475873672e5ed9071b31630c193cb84b2e747d14f3d14acf6' 
  AND token = 'hi4TQmaGbitpOXrHEuiBWeSLum1mOYguhlNrh9UyspU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}