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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a5a4883d270391ab1834a35c81e46d202f4190ea6cf36e06bb7c1d9b69a233' 
  AND token = 'cyj4aRMaeoaQ1lmKRIGefD01uSVANNHH8nlgm3e14pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}