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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a9a87b4b0a43cac4d528875c96a19b8ed85e53baf271dec678e640ebcec210' 
  AND token = 'z0WkHsGJMGlI+wlLXxMzCJ0w7xexkv7xUjp+Erw0Ui4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}