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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37cbb04282c72af8985dec13269ebd78691411066eabb69653ffab38ea2fc33' 
  AND token = 'E9kJAeYAMItyO2XD54uxCEuIgi6xXEnhTzzCEdwgVqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}