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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'accd7e700a282c27555232a17bd02d4971a3632826d85408cd03dbbf0cdeae4f' 
  AND token = 'LFQRpAeINOPL1LfjqdRP1+hmYPnTb3kqhCSytxeLnt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}