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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7739c494067bd5c3503c3e274a9d6babe56230a6d1ff6eece4b3e1a8a43c47e1' 
  AND token = 'WYJ1wMAOu3m+AdE+aV5FB5bE3Pf810VS4SbhJe2PvAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}