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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebfd2e4545bc2b72dddab8f55bed36e22815ecac166d815d60ad4a713aa76267' 
  AND token = 'vZ5VLJUG7H7fYd/iIxP/QVsaQXQQo3440aZfndmFnjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}