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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fbb145e6040c687780386eeee5a506f455eb4c04fcc62b9d69abf7b8d2a5b25' 
  AND token = 'aBl2NYtTOaLAPk+cmaJc51aAmyxQ+qJu5+sF29a28HQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}