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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a104450528a1b009400e2762e3d7648283066c69a81faa3f6e8738a661c6bfdc' 
  AND token = 'BRijqbqcFjUoHiLxS2be5BzemQgpbJAAdYHdyjiqBXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}