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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5625177a069832bdf6e5fef6d5351e7e05495f36e262557a724f43f75eff5a' 
  AND token = 'cfOG8encNrrIW0T7XJpQM2D2XjoXXE2Y4qoA9MeXYV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}