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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1623b8843cd8f699366a1a0d6cb1eb4e20e2dfe6da8b1952b1ed8dabaa4c8c72' 
  AND token = 'kvt/0kTxvbPFX2pfDJ6kxpjAjZal47Wv/sdeD3ZBG00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}