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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75cd2caca2fb48aa66c2d48de729a96063567002169b98adb6824bd404c11d10' 
  AND token = 'qTESyn3TG/rT/uAPQB+0juOMtEwexcJ2xM12/O84GE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}