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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de60d28ce5151d6c3a1e4726bce3ea1e5147519ad0396e6d6adc6b1989eeefec' 
  AND token = 'o+5psGmSWOV8wXTTWgSWyNkrmdA5aNuFZ/8lK4RS8SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}