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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd3dd2175e4eb879012e61ef3db7a0a338c63a74d557e24999f64132e3ed2169' 
  AND token = '+nT4G+MEwjVut+4LhRsWCOofFuhThWRr/iCm78CFDWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}