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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641a99d1851f64713bed78b422f6fbf41bebc28cab468bdd58cbc70ef0788a58' 
  AND token = 'XTO8jyp0FwyyNT8wJO2am1SjGtDo5jZysLWyPuFzMBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}