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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02a99587eb3f938344c1a497508b1d69ed24aac46a268691aafcb50f196a3758' 
  AND token = 'YXq7Nfc8mEi+C3YwcO0CldIAYeG0fW1lWOVWpJ+Z2D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}