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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81bcdaf314bd3961db40289a6ec7197138e38ec2771daba9726425c0167ea77' 
  AND token = '2e+7lSGOoM3LWxN0UthdfotyB/IzZRJfAu9l+OY8/MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}