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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e21a47c85a7c981fb07224cef5b6fb23016e8f5993b6865758c74d5fa18194' 
  AND token = '+0h3DJLBbosHDV2wwx3gSGb6kaMXxG21lVd73cHgtj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}