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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da6d120b8f6b066f179b27d753d630e0e1013a3c8ef3d8a0804b0c459f65cf22' 
  AND token = 'MxkZd6gvpSv/11/Ob9Em1g6UmzDOlqcDB95kDgRzaOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}